In this new tutorial, we will show you how to use different PlayMolecule apps to explore the chemical space nearby LSD starting from this structure with the 5HT2-B receptor. We will then use LSD as a template to generate a small library of analogs and, finally, we will prepare the structures, set up a 3D docking HTVS and inspect any interesting compounds that may arise from this campaign.

Let ‘s get started!